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MicroRNA biogenesis pathways in cancer
MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and overexpression of individual ‘oncomiRs’ or genetic loss of tumour suppressor miRNAs are associated with human cancer and are sufficient to drive tumorigenesis in mouse models. Furthermore, global miRNA depletion caused...
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| Udgivet i: | Nat Rev Cancer |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859809/ https://ncbi.nlm.nih.gov/pubmed/25998712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3932 |
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