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MicroRNA biogenesis pathways in cancer

MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and overexpression of individual ‘oncomiRs’ or genetic loss of tumour suppressor miRNAs are associated with human cancer and are sufficient to drive tumorigenesis in mouse models. Furthermore, global miRNA depletion caused...

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Bibliografske podrobnosti
izdano v:Nat Rev Cancer
Main Authors: Lin, Shuibin, Gregory, Richard I.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859809/
https://ncbi.nlm.nih.gov/pubmed/25998712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3932
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