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MicroRNA biogenesis pathways in cancer
MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and overexpression of individual ‘oncomiRs’ or genetic loss of tumour suppressor miRNAs are associated with human cancer and are sufficient to drive tumorigenesis in mouse models. Furthermore, global miRNA depletion caused...
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| Publicado no: | Nat Rev Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859809/ https://ncbi.nlm.nih.gov/pubmed/25998712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3932 |
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