Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry

BACKGROUND: MicroRNAs (miRNA) regulate breast biology by binding to specific RNA sequences, leading to RNA degradation and inhibition of translation of their target genes. While germline genetic variations may disrupt some of these interactions between miRNAs and their targets, studies assessing the...

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Publicado no:Hum Genet
Main Authors: Qian, Frank, Feng, Ye, Zheng, Yonglan, Ogundiran, Temidayo O., Ojengbede, Oladosu, Zheng, Wei, Blot, William, Ambrosone, Christine B., John, Esther M., Bernstein, Leslie, Hu, Jennifer J., Ziegler, Regina G., Nyante, Sarah, Bandera, Elisa V., Ingles, Sue A., Press, Michael F., Nathanson, Katherine L., Hennis, Anselm, Nemesure, Barbara, Ambs, Stefan, Kolonel, Laurence N., Olopade, Olufunmilayo I., Haiman, Christopher A., Huo, Dezheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021583/
https://ncbi.nlm.nih.gov/pubmed/27380242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1707-1
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