Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus

CD4 tropism is conserved among all primate lentiviruses and likely contributes to viral pathogenesis by targeting cells that are critical for adaptive antiviral immune responses. Although CD4-independent variants of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) have been...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Swanstrom, Adrienne E., Haggarty, Beth, Jordan, Andrea P. O., Romano, Josephine, Leslie, George J., Aye, Pyone P., Marx, Preston A., Lackner, Andrew A., Del Prete, Gregory Q., Robinson, James E., Betts, Michael R., Montefiori, David C., LaBranche, Celia C., Hoxie, James A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859711/
https://ncbi.nlm.nih.gov/pubmed/26937037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02851-15
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