Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus

CD4 tropism is conserved among all primate lentiviruses and likely contributes to viral pathogenesis by targeting cells that are critical for adaptive antiviral immune responses. Although CD4-independent variants of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) have been...

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Bibliographic Details
Published in:J Virol
Main Authors: Swanstrom, Adrienne E., Haggarty, Beth, Jordan, Andrea P. O., Romano, Josephine, Leslie, George J., Aye, Pyone P., Marx, Preston A., Lackner, Andrew A., Del Prete, Gregory Q., Robinson, James E., Betts, Michael R., Montefiori, David C., LaBranche, Celia C., Hoxie, James A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859711/
https://ncbi.nlm.nih.gov/pubmed/26937037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02851-15
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