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PrP(Sc)-Specific Antibody Reveals C-Terminal Conformational Differences between Prion Strains

Understanding the structure of PrP(Sc) and its strain variation has been one of the major challenges in prion disease biology. To study the strain-dependent conformations of PrP(Sc), we purified proteinase-resistant PrP(Sc) (PrP(RES)) from mouse brains with three different murine-adapted scrapie str...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Saijo, Eri, Hughson, Andrew G., Raymond, Gregory J., Suzuki, Akio, Horiuchi, Motohiro, Caughey, Byron
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859706/
https://ncbi.nlm.nih.gov/pubmed/26937029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00088-16
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