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PrP(Sc)-Specific Antibody Reveals C-Terminal Conformational Differences between Prion Strains
Understanding the structure of PrP(Sc) and its strain variation has been one of the major challenges in prion disease biology. To study the strain-dependent conformations of PrP(Sc), we purified proteinase-resistant PrP(Sc) (PrP(RES)) from mouse brains with three different murine-adapted scrapie str...
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| Опубликовано в: : | J Virol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859706/ https://ncbi.nlm.nih.gov/pubmed/26937029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00088-16 |
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