PrP(Sc)-Specific Antibody Reveals C-Terminal Conformational Differences between Prion Strains

Understanding the structure of PrP(Sc) and its strain variation has been one of the major challenges in prion disease biology. To study the strain-dependent conformations of PrP(Sc), we purified proteinase-resistant PrP(Sc) (PrP(RES)) from mouse brains with three different murine-adapted scrapie str...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Saijo, Eri, Hughson, Andrew G., Raymond, Gregory J., Suzuki, Akio, Horiuchi, Motohiro, Caughey, Byron
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Prions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859706/
https://ncbi.nlm.nih.gov/pubmed/26937029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00088-16
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