Preserved Autonomic Cardiovascular Regulation With Cardiac Pacemaker Inhibition: A Crossover Trial Using High‐Fidelity Cardiovascular Phenotyping

BACKGROUND: Sympathetic and parasympathetic influences on heart rate (HR), which are governed by baroreflex mechanisms, are integrated at the cardiac sinus node through hyperpolarization‐activated cyclic nucleotide–gated channels (HCN4). We hypothesized that HCN4 blockade with ivabradine selectively...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Heusser, Karsten, Tank, Jens, Brinkmann, Julia, Schroeder, Christoph, May, Marcus, Großhennig, Anika, Wenzel, Daniela, Diedrich, André, Sweep, Fred C. G. J., Mehling, Heidrun, Luft, Friedrich C., Jordan, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859385/
https://ncbi.nlm.nih.gov/pubmed/26764413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002674
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