Preserved Autonomic Cardiovascular Regulation With Cardiac Pacemaker Inhibition: A Crossover Trial Using High‐Fidelity Cardiovascular Phenotyping

BACKGROUND: Sympathetic and parasympathetic influences on heart rate (HR), which are governed by baroreflex mechanisms, are integrated at the cardiac sinus node through hyperpolarization‐activated cyclic nucleotide–gated channels (HCN4). We hypothesized that HCN4 blockade with ivabradine selectively...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Heusser, Karsten, Tank, Jens, Brinkmann, Julia, Schroeder, Christoph, May, Marcus, Großhennig, Anika, Wenzel, Daniela, Diedrich, André, Sweep, Fred C. G. J., Mehling, Heidrun, Luft, Friedrich C., Jordan, Jens
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859385/
https://ncbi.nlm.nih.gov/pubmed/26764413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002674
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