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The F-box Protein Rcy1 Is Involved in the Degradation of Histone H3 Variant Cse4 and Genome Maintenance

Cse4, a histone H3-like centromeric protein, plays critical functions in chromosome segregation. Cse4 level is tightly regulated, but the underlying mechanism remains poorly understood. We employed a toxicity-based screen to look for the degradation components involved in Cse4 regulation. Here, we s...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cheng, Haili, Bao, Xin, Rao, Hai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858983/
https://ncbi.nlm.nih.gov/pubmed/26975376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.701813
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