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Quantification of Cooperativity in Heterodimer-DNA Binding Improves the Accuracy of Binding Specificity Models
Many transcription factors (TFs) have the ability to cooperate on DNA elements as heterodimers. Despite the significance of TF heterodimerization for gene regulation, a quantitative understanding of cooperativity between various TF dimer partners and its impact on heterodimer DNA binding specificity...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858977/ https://ncbi.nlm.nih.gov/pubmed/26912662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691154 |
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