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Loss of Mitochondrial Function Impairs Lysosomes

Alterations in mitochondrial function, as observed in neurodegenerative diseases, lead to disrupted energy metabolism and production of damaging reactive oxygen species. Here, we demonstrate that mitochondrial dysfunction also disrupts the structure and function of lysosomes, the main degradation an...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Demers-Lamarche, Julie, Guillebaud, Gérald, Tlili, Mouna, Todkar, Kiran, Bélanger, Noémie, Grondin, Martine, Nguyen, Angela P., Michel, Jennifer, Germain, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858975/
https://ncbi.nlm.nih.gov/pubmed/26987902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695825
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