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Bifunctional CYP81AA proteins catalyse identical hydroxylations but alternative regioselective phenol couplings in plant xanthone biosynthesis

Xanthones are natural products present in plants and microorganisms. In plants, their biosynthesis starts with regioselective cyclization of 2,3′,4,6-tetrahydroxybenzophenone to either 1,3,5- or 1,3,7-trihydroxyxanthones, catalysed by cytochrome P450 (CYP) enzymes. Here we isolate and express CYP81A...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: El-Awaad, Islam, Bocola, Marco, Beuerle, Till, Liu, Benye, Beerhues, Ludger
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858744/
https://ncbi.nlm.nih.gov/pubmed/27145837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11472
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