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A Single Amino Acid Substitution Converts Benzophenone Synthase into Phenylpyrone Synthase

Benzophenone metabolism provides a number of plant natural products with fascinating chemical structures and intriguing pharmacological activities. Formation of the carbon skeleton of benzophenone derivatives from benzoyl-CoA and three molecules of malonyl-CoA is catalyzed by benzophenone synthase (...

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Autores principales: Klundt, Tim, Bocola, Marco, Lütge, Maren, Beuerle, Till, Liu, Benye, Beerhues, Ludger
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781496/
https://ncbi.nlm.nih.gov/pubmed/19710020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038927
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