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STIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart

In non-excitable cells stromal interaction molecule 1 (STIM1) is a key element in the generation of Ca(2+) signals that lead to gene expression, migration and cell proliferation. A growing body of literature suggests that STIM1 plays a key role in the development of pathological cardiac hypertrophy....

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Bibliographic Details
Published in:Sci Rep
Main Authors: Parks, Cory, Alam, Mohammad Afaque, Sullivan, Ryan, Mancarella, Salvatore
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858716/
https://ncbi.nlm.nih.gov/pubmed/27150728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25372
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