Simplified quantification method for in vivo SPECT/CT imaging of asialoglycoprotein receptor with (99m)Tc-p(VLA-co-VNI) to assess and stage hepatic fibrosis in mice

The goal of this study is to develop a noninvasive method of SPECT imaging to quantify and stage liver fibrosis with an Asialoglycoprotein receptor (ASGP-R) targeting tracer—(99m)Tc-p(VLA-co-VNI). ASGP-Rs are well known to specifically express in the mammalian liver. Here, we demonstrated ASGP-R exp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Deliang, Guo, Zhide, Zhang, Pu, Li, Yesen, Su, Xinhui, You, Linyi, Gao, Mengna, Liu, Chang, Wu, Hua, Zhang, Xianzhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858650/
https://ncbi.nlm.nih.gov/pubmed/27150943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25377
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