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GNAS gene mutation may be present only transiently during colorectal tumorigenesis

Mutations of the gene GNAS have been shown to activate the adenylate cyclase gene and lead to constitutive cAMP signaling. Several preliminary reports have suggested a role for GNAS gene mutations during colorectal carcinogenesis, particularly mucinous carcinomas. The aim of this study was to clarif...

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Detalhes bibliográficos
Publicado no:Int J Mol Epidemiol Genet
Main Authors: Zauber, Peter, Marotta, Stephen P, Sabbath-Solitare, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858613/
https://ncbi.nlm.nih.gov/pubmed/27186325
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