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GNAS gene mutation may be present only transiently during colorectal tumorigenesis

Mutations of the gene GNAS have been shown to activate the adenylate cyclase gene and lead to constitutive cAMP signaling. Several preliminary reports have suggested a role for GNAS gene mutations during colorectal carcinogenesis, particularly mucinous carcinomas. The aim of this study was to clarif...

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Vydáno v:Int J Mol Epidemiol Genet
Hlavní autoři: Zauber, Peter, Marotta, Stephen P, Sabbath-Solitare, Marlene
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858613/
https://ncbi.nlm.nih.gov/pubmed/27186325
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