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Unlocking the secrets to protein–protein interface drug targets using structural mass spectrometry techniques
Protein–protein interactions (PPIs) drive all biologic systems at the subcellular and extracellular level. Changes in the specificity and affinity of these interactions can lead to cellular malfunctions and disease. Consequently, the binding interfaces between interacting protein partners are import...
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| Publicat a: | Expert Rev Proteomics |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858316/ https://ncbi.nlm.nih.gov/pubmed/26400464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14789450.2015.1079487 |
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