A Regional Reduction in I(to) and I(KACh) in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity

BACKGROUND: The left atrial posterior wall (LAPW) is potentially an important area for the development and maintenance of atrial fibrillation. We assessed whether there are regional electrical differences throughout the murine left atrial myocardium that could underlie regional differences in arrhyt...

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Udgivet i:PLoS One
Main Authors: Holmes, Andrew P., Yu, Ting Y., Tull, Samantha, Syeda, Fahima, Kuhlmann, Stefan M., O’Brien, Sian-Marie, Patel, Pushpa, Brain, Keith L., Pavlovic, Davor, Brown, Nigel A., Fabritz, Larissa, Kirchhof, Paulus
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858288/
https://ncbi.nlm.nih.gov/pubmed/27149380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154077
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