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Initial characterization of a dually radiolabeled peptide for simultaneous monitoring of protein targets and enzymatic activity

OBJECTIVE: The goal of this study was to develop dually radiolabeled peptides for simultaneous imaging of cancer cell localization by targeting the α(v)β(3) integrin and their pathophysiology by targeting the activity of the proteolytic enzyme MMP2, involved in the metastatic process. METHODS: A hyb...

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Publicat a:Nucl Med Biol
Autors principals: Mebrahtu, Efrem, Zheleznyak, Alexander, Hur, Minjun A., Laforest, Richard, Lapi, Suzanne E.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857598/
https://ncbi.nlm.nih.gov/pubmed/23154178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.10.003
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