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Initial characterization of a dually radiolabeled peptide for simultaneous monitoring of protein targets and enzymatic activity

OBJECTIVE: The goal of this study was to develop dually radiolabeled peptides for simultaneous imaging of cancer cell localization by targeting the α(v)β(3) integrin and their pathophysiology by targeting the activity of the proteolytic enzyme MMP2, involved in the metastatic process. METHODS: A hyb...

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Detalhes bibliográficos
Publicado no:Nucl Med Biol
Main Authors: Mebrahtu, Efrem, Zheleznyak, Alexander, Hur, Minjun A., Laforest, Richard, Lapi, Suzanne E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857598/
https://ncbi.nlm.nih.gov/pubmed/23154178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.10.003
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