Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors

AIM: Aberrant c-Met activation plays a critical role in cancer formation, progression and dissemination, as well as in development of resistance to anticancer drugs. Therefore, c-Met has emerged as an attractive target for cancer therapy. The aim of this study was to develop new c-Met inhibitors and...

Full description

Saved in:
Bibliographic Details
Published in:Acta Pharmacol Sin
Main Authors: Liu, Tong-chao, Peng, Xia, Ma, Yu-chi, Ji, Yin-chun, Chen, Dan-qi, Zheng, Ming-yue, Zhao, Dong-mei, Cheng, Mao-sheng, Geng, Mei-yu, Shen, Jing-kang, Ai, Jing, Xiong, Bing
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857548/
https://ncbi.nlm.nih.gov/pubmed/27041462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.11
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items