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Carbocisteine attenuates TNF-α-induced inflammation in human alveolar epithelial cells in vitro through suppressing NF-κB and ERK1/2 MAPK signaling pathways

AIM: We previously proven that carbocisteine, a conventional mucolytic drug, remarkably reduced the rate of acute exacerbations and improved the quality of life in the patients with chronic obstructive pulmonary disease. In this study we investigated the mechanisms underlying the anti-inflammatory e...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Acta Pharmacol Sin
Päätekijät: Wang, Wei, Guan, Wei-jie, Huang, Rong-quan, Xie, Yan-qing, Zheng, Jin-ping, Zhu, Shao-xuan, Chen, Mao, Zhong, Nan-shan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857541/
https://ncbi.nlm.nih.gov/pubmed/26997568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.150
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