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Synthesis of 7-Aminocoumarin by Buchwald–Hartwig Cross Coupling for Specific Protein Labeling in Living Cells

PRIME time: We report the synthesis of a pH-insensitive blue fluorophore, 7-aminocoumarin, by using palladium-catalyzed Buchwald–Hartwig cross coupling. 7-Aminocoumarin can be used to tag recombinant proteins on the cell surface and inside living cells through PRIME (probe incorporation mediated by...

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Dettagli Bibliografici
Pubblicato in:Chembiochem
Autori principali: Jin, Xin, Uttamapinant, Chayasith, Ting, Alice Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857190/
https://ncbi.nlm.nih.gov/pubmed/21154801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000414
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