Nonhematopoietic Nrf2 dominantly impedes adult progression of sickle cell anemia in mice

The prevention of organ damage and early death in young adults is a major clinical concern in sickle cell disease (SCD). However, mechanisms that control adult progression of SCD during the transition from adolescence are poorly defined with no cognate prophylaxis. Here, we demonstrate in a longitud...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Ghosh, Samit, Ihunnah, Chibueze A., Hazra, Rimi, Walker, Aisha L., Hansen, Jason M., Archer, David R., Owusu-Ansah, Amma T., Ofori-Acquah, Solomon F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857015/
https://ncbi.nlm.nih.gov/pubmed/27158670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.81090
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