Polymorphic tandem repeats within gene promoters act as modifiers of gene expression and DNA methylation in humans

Despite representing an important source of genetic variation, tandem repeats (TRs) remain poorly studied due to technical difficulties. We hypothesized that TRs can operate as expression (eQTLs) and methylation (mQTLs) quantitative trait loci. To test this we analyzed the effect of variation at 484...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Quilez, Javier, Guilmatre, Audrey, Garg, Paras, Highnam, Gareth, Gymrek, Melissa, Erlich, Yaniv, Joshi, Ricky S., Mittelman, David, Sharp, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Genomics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857002/
https://ncbi.nlm.nih.gov/pubmed/27060133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw219
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items