טוען...

Polymorphic tandem repeats within gene promoters act as modifiers of gene expression and DNA methylation in humans

Despite representing an important source of genetic variation, tandem repeats (TRs) remain poorly studied due to technical difficulties. We hypothesized that TRs can operate as expression (eQTLs) and methylation (mQTLs) quantitative trait loci. To test this we analyzed the effect of variation at 484...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nucleic Acids Res
Main Authors: Quilez, Javier, Guilmatre, Audrey, Garg, Paras, Highnam, Gareth, Gymrek, Melissa, Erlich, Yaniv, Joshi, Ricky S., Mittelman, David, Sharp, Andrew J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857002/
https://ncbi.nlm.nih.gov/pubmed/27060133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw219
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!