An essential role for UTX in resolution and activation of bivalent promoters

Trimethylated histone H3 lysine 27 (H3K27me3) is linked to gene silencing, whereas H3K4me3 is associated with gene activation. These two marks frequently co-occupy gene promoters, forming bivalent domains. Bivalency signifies repressed but activatable states of gene expression and can be resolved to...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Dhar, Shilpa S., Lee, Sung-Hun, Chen, Kaifu, Zhu, Guangjing, Oh, WonKyung, Allton, Kendra, Gafni, Ohad, Kim, Young Zoon, Tomoiga, Alin S., Barton, Michelle Craig, Hanna, Jacob H., Wang, Zhibin, Li, Wei, Lee, Min Gyu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
Gene regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856969/
https://ncbi.nlm.nih.gov/pubmed/26762983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1516
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