An essential role for UTX in resolution and activation of bivalent promoters

Trimethylated histone H3 lysine 27 (H3K27me3) is linked to gene silencing, whereas H3K4me3 is associated with gene activation. These two marks frequently co-occupy gene promoters, forming bivalent domains. Bivalency signifies repressed but activatable states of gene expression and can be resolved to...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Dhar, Shilpa S., Lee, Sung-Hun, Chen, Kaifu, Zhu, Guangjing, Oh, WonKyung, Allton, Kendra, Gafni, Ohad, Kim, Young Zoon, Tomoiga, Alin S., Barton, Michelle Craig, Hanna, Jacob H., Wang, Zhibin, Li, Wei, Lee, Min Gyu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2016
Aiheet:
Gene regulation, Chromatin and Epigenetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856969/
https://ncbi.nlm.nih.gov/pubmed/26762983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1516
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