An essential role for UTX in resolution and activation of bivalent promoters

Trimethylated histone H3 lysine 27 (H3K27me3) is linked to gene silencing, whereas H3K4me3 is associated with gene activation. These two marks frequently co-occupy gene promoters, forming bivalent domains. Bivalency signifies repressed but activatable states of gene expression and can be resolved to...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Dhar, Shilpa S., Lee, Sung-Hun, Chen, Kaifu, Zhu, Guangjing, Oh, WonKyung, Allton, Kendra, Gafni, Ohad, Kim, Young Zoon, Tomoiga, Alin S., Barton, Michelle Craig, Hanna, Jacob H., Wang, Zhibin, Li, Wei, Lee, Min Gyu
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856969/
https://ncbi.nlm.nih.gov/pubmed/26762983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1516
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