An essential role for UTX in resolution and activation of bivalent promoters

Trimethylated histone H3 lysine 27 (H3K27me3) is linked to gene silencing, whereas H3K4me3 is associated with gene activation. These two marks frequently co-occupy gene promoters, forming bivalent domains. Bivalency signifies repressed but activatable states of gene expression and can be resolved to...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Dhar, Shilpa S., Lee, Sung-Hun, Chen, Kaifu, Zhu, Guangjing, Oh, WonKyung, Allton, Kendra, Gafni, Ohad, Kim, Young Zoon, Tomoiga, Alin S., Barton, Michelle Craig, Hanna, Jacob H., Wang, Zhibin, Li, Wei, Lee, Min Gyu
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856969/
https://ncbi.nlm.nih.gov/pubmed/26762983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1516
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