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The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases
High mobility group box 1 (HMGB1) is a nuclear protein that can bind to DNA and act as a co-factor for gene transcription. When released into extracellular fluid, it plays a proinflammatory role by acting as a damage-associated molecular pattern molecule (DAMP) (also known as an alarmin) to initiate...
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| Publicado en: | Acta Pharm Sin B |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856949/ https://ncbi.nlm.nih.gov/pubmed/27175328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.02.004 |
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