The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases

High mobility group box 1 (HMGB1) is a nuclear protein that can bind to DNA and act as a co-factor for gene transcription. When released into extracellular fluid, it plays a proinflammatory role by acting as a damage-associated molecular pattern molecule (DAMP) (also known as an alarmin) to initiate...

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Bibliografiska uppgifter
I publikationen:Acta Pharm Sin B
Huvudupphovsmän: Chen, Qingjie, Guan, Xiaofeng, Zuo, Xiaocong, Wang, Jianglin, Yin, Wenjun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856949/
https://ncbi.nlm.nih.gov/pubmed/27175328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.02.004
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