Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder

Alzheimer's disease (AD) is an age-related neurodegenerative disorder that displays pathological characteristics including senile plaques and neurofibrillary tangles. Metabolic defects are also present in AD-brain: for example, signs of deficient cerebral glucose uptake may occur decades before...

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Publicat a:Biochim Biophys Acta
Autors principals: Xu, Jingshu, Begley, Paul, Church, Stephanie J., Patassini, Stefano, Hollywood, Katherine A., Jüllig, Mia, Curtis, Maurice A., Waldvogel, Henry J., Faull, Richard L.M., Unwin, Richard D., Cooper, Garth J.S.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Pub. Co 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856736/
https://ncbi.nlm.nih.gov/pubmed/26957286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.03.001
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