Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease

Ob/ob mice provide an animal model for non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH) in patients with obesity and type-2 diabetes. Low liver copper has been linked to hepatic lipid build-up (steatosis) in animals with systemic copper deficiency caused by low-copper die...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Church, Stephanie J., Begley, Paul, Kureishy, Nina, McHarg, Selina, Bishop, Paul N., Bechtold, David A., Unwin, Richard D., Cooper, Garth J.S.
Format: Artigo
Langue:Inglês
Publié: Academic Press 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427106/
https://ncbi.nlm.nih.gov/pubmed/25797622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.03.067
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires