Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation

BACKGROUND: Heart disease is the leading cause of death in diabetic patients, and defective copper metabolism may play important roles in the pathogenesis of diabetic cardiomyopathy (DCM). The present study sought to determine how myocardial copper status and key copper-proteins might become impaire...

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Detalhes bibliográficos
Main Authors: Zhang, Shaoping, Liu, Hong, Amarsingh, Greeshma V, Cheung, Carlos C H, Hogl, Sebastian, Narayanan, Umayal, Zhang, Lin, McHarg, Selina, Xu, Jingshu, Gong, Deming, Kennedy, John, Barry, Bernard, Choong, Yee Soon, Phillips, Anthony R J, Cooper, Garth J S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070334/
https://ncbi.nlm.nih.gov/pubmed/24927960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-100
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