CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1- induced T cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is a high-risk subset of acute leukemia, characterized by frequent activation of Notch1 or AKT signaling, where new_therapeutic approaches are needed. We showed previously that Cyclin-dependent kinase 6 (CDK6) is required for thymic lymphoblastic lymphoma...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Jena, Nilamani, Sheng, Jinghao, Hu, Jamie K., Li, Wei, Zhou, Wenhui, Lee, Gene, Tsichlis, Nicolaos, Pathak, Aparna, Brown, Nelson, Deshpande, Amit, Luo, Chi, Hu, Guo-fu, Hinds, Philip W., Van Etten, Richard A., Hu, Miaofen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856559/
https://ncbi.nlm.nih.gov/pubmed/26707936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.353
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados