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CDK6 inhibits white to beige fat transition by suppressing RUNX1
Whereas white adipose tissue depots contribute to the development of metabolic diseases, brown and beige adipose tissue has beneficial metabolic effects. Here we show that CDK6 regulates beige adipocyte formation. We demonstrate that mice lacking the CDK6 protein or its kinase domain (K43M) exhibit...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5845007/ https://ncbi.nlm.nih.gov/pubmed/29523786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03451-1 |
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