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Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5

Fbxo30 is an orphan member of the F-box protein family with no known substrate or function. Here, we report that while Fbxo30(−/−) mice exhibit normal development, growth, life span, and fertility, the females fail to nurture their offspring due to defective mammopoiesis. Mass spectrometry analysis...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Liu, Yan, Wang, Yin, Du, Zhanwen, Yan, Xiaoli, Zheng, Pan, Liu, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856546/
https://ncbi.nlm.nih.gov/pubmed/27117404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.083
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