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Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs

GRP78, a member of the ER stress protein family, can relocate to the surface of cancer cells, playing key roles in promoting cell proliferation and metastasis. GRP78 consists of two major functional domains: the ATPase and protein/peptide-binding domains. The protein/peptide-binding domain of cell-s...

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Foilsithe in:PLoS One
Main Authors: Hughes, Scott J., Antoshchenko, Tetyana, Chen, Yun, Lu, Hua, Pizarro, Juan C., Park, Hee-Won
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856263/
https://ncbi.nlm.nih.gov/pubmed/27144892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154862
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