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Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs
GRP78, a member of the ER stress protein family, can relocate to the surface of cancer cells, playing key roles in promoting cell proliferation and metastasis. GRP78 consists of two major functional domains: the ATPase and protein/peptide-binding domains. The protein/peptide-binding domain of cell-s...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856263/ https://ncbi.nlm.nih.gov/pubmed/27144892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154862 |
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