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Systems analysis reveals down-regulation of a network of pro-survival miRNAs drives the apoptotic response in dilated cardiomyopathy

Apoptosis is a hallmark of multiple etiologies of heart failure, including dilated cardiomyopathy. Since microRNAs are master regulators of cardiac development and key effectors of intracellular signaling, they represent novel candidates for understanding the mechanisms driving the increased dysfunc...

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Detalhes bibliográficos
Publicado no:Mol Biosyst
Main Authors: Isserlin, Ruth, Merico, Daniele, Wang, Dingyan, Vuckovic, Dajana, Bousette, Nicolas, Gramolini, Anthony O., Bader, Gary D., Emili, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856157/
https://ncbi.nlm.nih.gov/pubmed/25361207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00265b
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