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Structures of C-mannosylated anti-adhesives bound to the type 1 fimbrial FimH adhesin
Selective inhibitors of the type 1 fimbrial adhesin FimH are recognized as attractive alternatives for antibiotic therapies and prophylaxes against Escherichia coli infections such as urinary-tract infections. To construct these inhibitors, the α-d-mannopyranoside of high-mannose N-glycans, recogniz...
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| Vydáno v: | IUCrJ |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
International Union of Crystallography
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856138/ https://ncbi.nlm.nih.gov/pubmed/27158502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252516002487 |
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