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A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier
The blood-brain barrier (BBB) protects the brain from toxic substances within the peripheral circulation. It maintains brain homeostasis and is a hurdle for drug delivery to the CNS to treat neurodegenerative diseases, including Alzheimer’s disease and brain tumors. The drug efflux transporter P-gly...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855938/ https://ncbi.nlm.nih.gov/pubmed/27043281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76207 |
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