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Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier
ATP-binding cassette (ABC) transporters are important, selective elements of the blood-brain barrier. They line the luminal plasma membrane of the brain capillary endothelium, facing the vascular space, both protecting the CNS from entry of neurotoxicants and limiting access of therapeutic drugs to...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882496/ https://ncbi.nlm.nih.gov/pubmed/20417575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2010.03.003 |
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