FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal

Recent studies in patients with ovarian cancer suggest that tumor growth may be accelerated following cessation of antiangiogenesis therapy; however, the underlying mechanisms are not well understood. In this study, we aimed to compare the effects of therapy withdrawal to those of continuous treatme...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Haemmerle, Monika, Bottsford-Miller, Justin, Pradeep, Sunila, Taylor, Morgan L., Choi, Hyun-Jin, Hansen, Jean M., Dalton, Heather J., Stone, Rebecca L., Cho, Min Soon, Nick, Alpa M., Nagaraja, Archana S., Gutschner, Tony, Gharpure, Kshipra M., Mangala, Lingegowda S., Rupaimoole, Rajesha, Han, Hee Dong, Zand, Behrouz, Armaiz-Pena, Guillermo N., Wu, Sherry Y., Pecot, Chad V., Burns, Alan R., Lopez-Berestein, Gabriel, Afshar-Kharghan, Vahid, Sood, Anil K.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855933/
https://ncbi.nlm.nih.gov/pubmed/27064283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85086
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