c-Met–mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma

Aberrant vascularization is a hallmark of cancer progression and treatment resistance. Here, we have shown that endothelial cell (EC) plasticity drives aberrant vascularization and chemoresistance in glioblastoma multiforme (GBM). By utilizing human patient specimens, as well as allograft and geneti...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Huang, Menggui, Liu, Tianrun, Ma, Peihong, Mitteer, R. Alan, Zhang, Zhenting, Kim, Hyun Jun, Yeo, Eujin, Zhang, Duo, Cai, Peiqiang, Li, Chunsheng, Zhang, Lin, Zhao, Botao, Roccograndi, Laura, O’Rourke, Donald M., Dahmane, Nadia, Gong, Yanqing, Koumenis, Constantinos, Fan, Yi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855929/
https://ncbi.nlm.nih.gov/pubmed/27043280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84876
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