c-Met–mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma

Aberrant vascularization is a hallmark of cancer progression and treatment resistance. Here, we have shown that endothelial cell (EC) plasticity drives aberrant vascularization and chemoresistance in glioblastoma multiforme (GBM). By utilizing human patient specimens, as well as allograft and geneti...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Huang, Menggui, Liu, Tianrun, Ma, Peihong, Mitteer, R. Alan, Zhang, Zhenting, Kim, Hyun Jun, Yeo, Eujin, Zhang, Duo, Cai, Peiqiang, Li, Chunsheng, Zhang, Lin, Zhao, Botao, Roccograndi, Laura, O’Rourke, Donald M., Dahmane, Nadia, Gong, Yanqing, Koumenis, Constantinos, Fan, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855929/
https://ncbi.nlm.nih.gov/pubmed/27043280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84876
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