Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines

We discuss the use of pluripotent stem cell lines carrying fluorescent reporters driven by retinal promoters to derive three-dimensional (3-D) retina in culture and how this system can be exploited for elucidating human retinal biology, creating disease models in a dish, and designing targeted drug...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Kaewkhaw, Rossukon, Swaroop, Manju, Homma, Kohei, Nakamura, Jutaro, Brooks, Matthew, Kaya, Koray Dogan, Chaitankar, Vijender, Michael, Sam, Tawa, Gregory, Zou, Jizhong, Rao, Mahendra, Zheng, Wei, Cogliati, Tiziana, Swaroop, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
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Special Issue
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855830/
https://ncbi.nlm.nih.gov/pubmed/27116668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17639
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