Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

Activation of quiescent hepatic stellate cells (HSCs) is the major event in hepatic fibrogenesis, along with enhancement of cell proliferation and overproduction of extracellular matrix. Although inhibition of cell proliferation and induction of apoptosis are potential strategies to block the activa...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jin, H, Lian, N, Zhang, F, Chen, L, Chen, Q, Lu, C, Bian, M, Shao, J, Wu, L, Zheng, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855671/
https://ncbi.nlm.nih.gov/pubmed/27077805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.92
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