Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

Activation of quiescent hepatic stellate cells (HSCs) is the major event in hepatic fibrogenesis, along with enhancement of cell proliferation and overproduction of extracellular matrix. Although inhibition of cell proliferation and induction of apoptosis are potential strategies to block the activa...

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Vydáno v:Cell Death Dis
Hlavní autoři: Jin, H, Lian, N, Zhang, F, Chen, L, Chen, Q, Lu, C, Bian, M, Shao, J, Wu, L, Zheng, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855671/
https://ncbi.nlm.nih.gov/pubmed/27077805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.92
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