Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis

OBJECTIVE: In the spondyloarthritides (SpA), increased numbers of CD4+ T cells express killer cell immunoglobulin‐like receptor 3DL2 (KIR‐3DL2). The aim of this study was to determine the factors that induce KIR‐3DL2 expression, and to characterize the relationship between HLA–B27 and the phenotype...

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Udgivet i:Arthritis Rheumatol
Main Authors: Ridley, Anna, Hatano, Hiroko, Wong‐Baeza, Isabel, Shaw, Jacqueline, Matthews, Katherine K., Al‐Mossawi, Hussein, Ladell, Kristin, Price, David A., Bowness, Paul, Kollnberger, Simon
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Spondyloarthritis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855641/
https://ncbi.nlm.nih.gov/pubmed/26841353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39515
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